Our Program in Computation Genomics Journal Club is starting again, now the 3rd Friday of each month. The next meeting is this Friday, April 16, at 3pm in the CHGR conference room. As usual, please bring in any articles you've found recently and give a brief overview of why you thought it was interesting.

Here are the papers we talked about in yesterday's Journal Club:Genome Biol. 2009; 10(11): R134Searching for SNPs with cloud computing.Langmead B, Schatz MC, Lin J, Pop M, Salzberg SL.Table of Contents, Nature Methods, Visualization Supplement.Am J Hum Genet.

If you read the previously mentioned "synthetic associations" paper in PLoS Bio by Dickson et al. in David Goldstein's group, be sure to read this brief commentary written by Pat Sullivan at UNC offering a different point of view.

Here are the papers we talked about in yesterday's Journal Club: PLoS Biol. 2010 Jan 26;8(1):e1000294. Rare variants create synthetic genome-wide associations. See my previous coverage of this paper and the comments. Dickson SP, Wang K, Krantz I, Hakonarson H, Goldstein DB. PLoS Genet. 2010 Jan;6(1):e1000798.

We're restarting the PCG Journal Club again Monday February 8 at 4pm in the CHGR conference room. Most of you who usually attend are familiar with the format, but if not, bring any papers you've read recently and give a brief (i.e. 2 minute) overview of the paper and why you thought it was interesting. No slides allowed.

There were only a couple of citations for articles discussed at this week's PCG meeting (September 11). Our next meeting is scheduled for September 26.~JuliaKim S, Xing EP. Statistical estimation of correlated genome associations to a quantitative trait network. PLoS Genet. 2009 Aug; 5(8):e1000587.Zamar D, Tripp B, Ellis G, Daley D. Path: a tool to failitate pathway-based genetic association analysis. Bioinformatics. 2009 Sep 15;

Here are citations for the articles discussed at our most recent meeting (August 28). I have also appended a link to Nature Reviews: Genetics new series, Fundamental concepts in genetics, at the end. Our next meeting is scheduled for September 11.~JuliaGurwitz D, Fortier I, Lunshof JE, Knoppers BM. Research ethics: Children and population biobanks. Science . 2009 Aug 14; 325(5942):818-9 Hastings PJ, Lupski JR, Rosenberg SM, Ira G.

Here are citations for the articles discussed at our most recent meeting (July 31). Our next meeting is scheduled for August 14.~JuliaBogdanowicz W, Allen M, Branicki W, Lembring M, Gajewska M, Kupiec T. Genetic identification of putative remains of the famous astronomer Nicolaus Copernicus.

Here are citations for the articles discussed at our most recent meeting (July 17). Our next meeting is scheduled for July 31.~JuliaBianconi G, Pin P, Marsili M. Assessing the relevance of node features for network structure.

Here are citations for the articles discussed at our most recent meeting (June 24). Our next meeting is scheduled for July 17.~JuliaChoi Y, Wijsman EM, Weir BS. Case-control association testing in the presence of unknown relationships. Genet Epidemiol . 2009 Mar 30. [Epub ahead of print]Gao X, Becker LC, Becker DM, Starmer JD, Province MA. Avoiding the high Bonferroni penalty in genome-wide association studies. Genet Epidemiol .