Biological SciencesSubstack

Paired Ends

Bioinformatics, computational biology, and data science updates from the field. Occasional posts on programming.
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R Biological Sciences
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Last night we had our first event in the newly (re-)launched Charlottesville R Users (CRU) group. We had about 30 or so attendees — about half from academia and half from industry, with a few from local government organizations.

PapersR AIBiological Sciences
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Happy Friday, colleagues. Lots going on this week. Once again I’m going through my long list of idle browser tabs trying to catch up where I can. ElevenReader (no affiliation) has been helpful to catch up this week! Subscribe now The Arc Institute reported the first ever viable genomes with genome language models.

Biological Sciences
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I recently came across this wonderful position paper by Olivia Guest and colleagues, where they pick apart the tech industry’s marketing, hype, & harm, arguing for safeguarding higher education, critical thinking, expertise, academic freedom, & scientific integrity. Guest, O., et al. Against the Uncritical Adoption of 'AI' Technologies in Academia. Zenodo, 5 Sept.

Biological Sciences
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I’ve spent years writing bioinformatics tools (I’ve spent the last 6 years in industry and 90% of these tools I’ll never publish or open-source) and building infectious disease forecasting models (most of these are open-source, like FOCUS for COVID-19 [paper, code], FIPHDE for influenza [paper, code], PLANES for forecast plausibility analysis [paper, code, blog post]). Anyone who has

Biological Sciences
Published

You upgrade your old Intel Macbook Pro for a new M4 MBP. You’re setting up a new cloud VM on AWS after migrating away from GCP. You get an account on your institution’s new HPC. You have everything just so in your development environment, and now you have to remember how to set everything up again. I just started a new position, and I’m doing this right now.

R NextflowAIPythonBiological Sciences
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Happy Friday, colleagues. Somehow it’s September (I did not approve of this). Lots going on this week, and this is my regular attempt to close out my browser tabs I’ve accumulated over the past week with blog posts, podcasts, papers, etc. in AI, data science, genomics, public health, programming, scicomm, and other miscellany.