Chris von Csefalvay is a computational epidemiologist/data scientist working at the intersection of AI, epidemiology and public health.

Around two years ago, almost to the day, I spent an absolutely frantic evening in Berkeley, going through enough coffee to power a mid-sized city, hammering away at my laptop on trying to figure out what comes after LLMs. What to most people was still barely on the horizon at the time has been a subject I have been working on in various capacities for the best part of the past decade, on and off.

Choral intelligences

When Pygmalion carved Galatea from ivory, he fell so deeply in love with his creation that he begged Aphrodite to bring her to life. The goddess, moved by his devotion, granted his wish.

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It’s a beautiful myth about art, obsession and the blurring lines between creation and creator. What the myth doesn’t tell us is whether Galatea charged a monthly subscription fee.

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Ovid,

 Metamorphoses

, Book 10, 243-297.

Love in the Time of Algorithms

There’s a cave in Ethiopia, in an area called Dikika. At some point, around 3.4 million years ago, an early hominin made some incisions on an animal carcass, leaving some notches on a bone as the makeshift knife cut past the muscle and sinew into the bone, tell-tale kerf marks that speak of the first time one of our ancestors used a tool.

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What happened in that cave changed everything for our species.

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McPherron, S.

A slow walk out of Dikika Cave

This is about the time of year when I get the sudden and irresistible urge to make kimchi.

Deep kimchi

Roughly 541 million years ago, something extraordinary happened in Earth’s oceans. Over a geologically brief period of perhaps 20 million years, the fossil record explodes with an almost obscene diversity of body plans.

Biome engineering

In 1790, the French Academy of Sciences commissioned a rather ambitious survey. The goal was to measure the distance from the North Pole to the Equator along the meridian passing through Paris, then use that measurement to define a new universal unit of length: the metre.

SOYA - the only benchmark that matters

In the first four entries (1 2 3 4) of this sequence, I have focused primarily on what LLMs aren’t, can’t, won’t, wouldn’t and shouldn’t. It’s probably time to conclude this series by that much awaited moment in all stories, where the darkest night finally turns into a glorious dawn, where we finally arrive at the promised land, where we finally get to talk about what LLMs

 could

be. What I see as the most successful potential model of

Teams of Rivals

Chris von Csefalvay

Over at the work blog, I’m discussing what knowledge means for large language models (LLMs), and the ways in which we can leverage this knowledge dividend for better inference.  Read the full post here.

Asemantic Induction of Hallucinations in LLMs

I love posts that allow me to merge some of my addictions.

Auto-DOI for Quarto posts via Rogue Scholar

The Department for Science, Innovation and Technology has just dropped its long-awaited AI Opportunities Action Plan, a 50-page vision of how the UK government plans to guide us into an AI-powered future.

Deja Vu, All Over Again.

The year is 1959. Eisenhower is on his second term, Castro just kicked Batista out of the country and Ray Charles’s Let the Good Times Roll is topping the charts.

The 95% myth

Say you’re busing tables and you’re trying to pass someone in a wheelchair. What do you do? Do you say “excuse me” and wait for them to move? Do you say “excuse me” and then try to pass them? Do you just try to pass them? Do you say nothing and just try to pass them? All of these are, actually, pretty legitimate answers. Now, say you’re a robot.

What I learned from getting bodied by a robot.

The knowledge dividend of large language models

When he first began his excavations at what is today Hisarlik in modern-day Türkiye, Heinrich Schliemann set out to find a single city – the city of Homer’s Iliad, a city many actually felt lay in the realms of fiction rather than any map he could lay his hands on. By the time excavations were over, Schliemann would find not one but nine cities, all built on top of each other.

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In that, he found something relatively common – cities

After agents

Yesterday, I completed a marathon on the SkiErg, with a pretty respectable time (see results here). I know I can do better, and I know I

 will

do better. On the other hand, this was a marathon where I pretty much did everything wrong. And that was sort of an instructive experience in its own right. The title is somewhat misleading. Not much went wrong – the marathon itself was smooth sailing.

How to do a SkiErg marathon entirely the wrong way (but still finish)

Every year, the Commandant of the Marine Corps publishes a reading list of books that often only bear on warfighting tangentially at best. The idea behind this is that those entrusted with the lives of servicemembers should have an understanding of the world that goes beyond the profession of arms. In much the same way, I have been advising data scientists to go beyond professional literature.

Five non-data-science books for data scientists

There’s a curious terminological schism that nobody talks about at what passes for dinner parties for the AI crowd.

Between the motion and the act

It appears that in what is clearly a wonderful little PR stunt, a Polish rum company managed to do a Sophia and appoint an ‘AI-driven’ ‘robot’ as its ‘CEO’.  The other guilty party to this pile of steaming bovine excrement is Hanson Robotics, famous for giving us Sophia, the “world’s first robot citizen”. Most of what I’m saying here goes just as well for Sophia.

The skeuomorphic fallacy

DeepSeek has been grabbing headlines in AI circles lately, showing up everywhere from Discord servers full of ML enthusiasts to LinkedIn posts where “thought leaders” tag each other in endless threads.

Seatbelts and straitjackets

If you spend any time on LinkedIn, it’s almost a certainty that you have come across a bevy of alleged ‘agentic AI architectures’. They all look something like this:     All very neat, but the audience might be forgiven for asking what exactly is agentic about this, except for relabeling subprocesses in what is a run-of-the-mill RPA workflow as ‘agents’. And the audience is, this once, perfectly right.

After agents, part 2 – Agents and the Agora

The awesome thing about language is that, well, we all mostly speak it, to some extent or another. This gives us an immensely powerful tool to manipulate transformational tasks. For the purposes of this post, I consider a transformational task to be essentially anything that takes an input and is largel intended to return some version of the same thing. This is not a very precise definition, but it will have to do for now.

LAIR - Language As Intermediate Representation

It’s not every day that you find out you have climbed the exalted heights of another discipline. My work is pretty interdisciplinary, but it shocked me, too, that I’m apparently holding forth on neoliberalism and the epistemic question in African universities (archive link):  This, of course, came at some surprise to me, as I have never written anything on the topic.

Stochastic parrots, cap and gown edition

The temple of Asclepios, the Greek god of healing arts and medicine, at Epidaurus was pretty much the ancient Greek world’s equivalent of the Mayo Clinic. It then tells us a lot about the Greek worldview of healing that one of the things the temple complex prominently featured was a theatre. The Greeks believed in drama therapy, but in perhaps a slightly different way of how we think of it today.

The Moral Pulse of the Machine

There’s a style of visual design I’m inordinately fond of called Raygun Gothic. It’s hard to describe what the hell exactly one needs to be on to enjoy it, but think of it like the aesthetic from the latter Fallout games with a more optimistic outlook on the future. Gibson described it as “the future that never was”, and I think that’s a pretty apt description. We get these competing futures in technology all the time.

Prompt Engineering: The Art of Yesterday

Tip If you’re here for the DOI matching script, the link is here. Quarto is a great tool for reproducible research. It is also a great tool for building websites. After about a decade of Wordpress-based websites, I’ve moved to Quarto primarily for two reasons. First, most of my content is largely static.

Quarto project scripts are awesomeness

I have probably spent more time looking at Poussin’s

 Dance to the Music of Time

than any other work of art. Sneaking off to the Wallace Collection in London and just looking at the

 Dance

was my comfort activity while living in London – a time that was not exactly devoid of its trials. It’s not, by any measure,

 great

art, insofar as such judgments can be made with any objectivity.

The Lyre of Hephaestus

There’s something special about language. It is ‘our own’, it is ‘us’, in a profound way, and quite surprisingly, more so than art. I was deeply struck by this when I first saw reactions to large generative language models that created realistic, human-ish prose.

Beyond Broca

In the middle of the green and pleasant countryside of England lies a small piece of commons –– land, that is, over which a number of people share certain rights. In this hypothetical scenario, it’s six farmers,  to . Each of them has a hypothetical cow, which differs from ordinary cows in that it grazes a fixed unit, and produces a fixed amount of milk (unlike real cows, which vary wildly in their input and output parameters, or so I’m told).

Ransomware attacks as n-person prisoner’s dilemmas

As I sit here at year’s end, I’m reminded of the ancient Swedish tradition of årsgång - the ritual winter walk taken on New Year’s Eve to divine the fortunes of the coming year.

Five unconventional predictions

My recent post on the Starschema blog discusses the need for better data products to tackle future pandemic challenges:  Read the full post here.

Data for the next pandemic

There’s a notion in artificial intelligence known as Moravec’s paradox: it’s relatively easy to teach a computer to play chess or checkers at a pretty decent level, but near impossible to teach it something as trivial as bipedal motion. (Hassabis 2017) The sensorimotor tasks that our truly wonderful brains have mastered by our second birthday are much harder to teach a computer than something arguably as ‘complex’ as beating a chess grandmaster.

The hardest AI problem you’ve never heard of.

As the new Omicron variant of concern of COVID-19 emerged over Thanksgiving week (of all times!), attention has been turning to Paxlovid (PF-07321332). If, like me, you torment yourself by perusing conspiracy theories, you might have heard it referred to as Pfizermectin.

Peace, love, Paxlovid and ‘Pfizermectin’

There might be valid concerns about the mRNA vaccines. Then there are the clearly insane ones, such as the claims that it involves the injection of a microchip. The argument that mRNA vaccines are a form of ‘gene therapy’ are somewhere in the middle, and that makes responding to it somewhat difficult.

Why the COVID-19 vaccines are not gene therapy

I used to be on Quora. I’m not anymore. But I used to be. And I wrote some answers. Here are some of my favourites, categorised by field… sort of.

 AI

If I wrote an AI and trained it to score 200 on a standardized IQ test, what could a human of 100 IQ still do better? Read the full answer here. Will true AI come before the ability to completely simulate a human brain? Is there a difference? Read the full answer here.

My favourite Quora answers

I’ve spent the better part of this weekend putting OpenAI’s latest offerings through their paces - both the newly released open-weight models and GPT-5 itself. Armed with a selection of coding challenges, mathematical problems, and the sort of esoteric research queries that usually separate the wheat from the chaff, I’ve been conducting what amounts to a weekend-long torture test of these systems.

The end of isotropy and the rise of metadynamic AI

In my latest post for the Starschema blog, I discuss the end of dashboards, and what comes next:  Read the full post here.

As we may see: the world after dashboards

When I read Andrej Karpathy’s endorsement of “context engineering” in a Twitter exchange with Shopify’s Tobi Lutke, I felt he tapped into something we all felt to some degree:  tweet={"url":"https:\/\/twitter.com\/karpathy\/status\/1937902205765607626","author_name":"Andrej Karpathy","author_url":"https:\/\/twitter.com\/karpathy","html":"\u003Cblockquote class=\"twitter-tweet\" align=\"center\"\u003E\u003Cp lang=\"en\" dir=\"ltr\"\u003E+1 for

The Snowmobile Symptom

There’s a pervasive problem with semantics in artificial intelligence. It’s present at the creation – the term itself characterises the subject as a man-made simulacrum of something ‘natural’ the way we speak of artificial flavourings and artificial rubber.

Just noise in the neurons

In a recent paper that has attracted the interest of popular media as well, Fabio Urbina and colleagues examined the use (or rather, the abuse) of computational chemistry models of toxicity for generating toxic compounds and potential chemical agent candidates.(Urbina et al. 2022) Urbina and colleagues conclude that Urbina, Fabio, Filippa Lentzos, Cédric Invernizzi, and Sean Ekins. 2022.

A different shade of grey

The Greeks

 loved

oracles. The average temple of Apollo, who among others was in charge of soothsaying and predictery, was adorned to the gills with gifts from grateful worshippers whose inscrutable questions got equally inscrutable answers from Apollo’s oracles. None of these were more famous than the Pythia, the young ladies high as a kite on volcanic fumes at Apollo’s temple in Delphi.