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Front Matter
The Front Matter Blog covers the intersection of science and technology since 2007.
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The legal disputes following the withdrawal from the market of two drugs for the treatment of pain (the COX-2 inhibitors rofecoxib and valdecoxib) have led to another critical examination of the paper publishing process. I have written in February about the drug company Pfizer trying to obtain confidential peer review documents from the journals JAMA and NEJM. Courts in Chicago and Boston have denied such requests.

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The new NIH Public Access policy started this past Monday. Fellow Nature Networker Graham Steel has summarized this week's reaction of the blogosphere. I would like to highlight some of the discussions we had here on Nature Network. Bob O'Hara wonders about the cost of publishing in Open Access: Show us the Money!. He argues that shifting the costs from reader to author can create problems.

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I did a little experiment to figure out whether the full-text versions of my last 15 papers (published between 1997-2008) are available online. The result: * 3 papers available for everybody * 10 papers only available from within my institution (Journal subscription required) * 2 papers only available for purchase Interestingly, the papers in the two journals with the highest impact factor are both available as full-text.

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Around Christmas, mandatory open access for NIH-funded research was signed into law: The Director of the National Institutes of Health shall require that all investigators funded by the NIH submit or have submitted for them to the National Library of Medicine's PubMed Central an electronic version of their final, peer-reviewed manuscripts upon acceptance for publication, to be made publicly available no later than 12 months after the official

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Erythropoietin is an effective drug to increase your number of red blood cells. It is primarily used in anemic patients with cancer and on dialysis, but it is also popular with athletes that want to (illegally) increase their endurance performance, most notably cyclists and cross country skiers.

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Participation in a social network can have it's perks. Thanks to the O'Reilly Group on Facebook (that other social network), I received a review copy of Wikipedia: The Missing Manual. But why would a scientist want to know how to write and edit articles on Wikipedia? Wikipedia has become a respectable source of information that rivals the more traditional encylopedias such as the Encyclopaedia Britannica.

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A March 13 Nature News article (Six degrees of messaging) talks about a study on Microsoft Messenger chat users. Any random two Microsoft Messenger users (out of about 240 million) could be connected two each other via an average of 6 users that have chatted with each other. This study is just another confirmation of the six degrees of separation concept.

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David Crotty, the Executive Editor from CSH Protocols, last month wrote a provocative blog post called Why Web 2.0 is failing in Biology. He did an informal poll among scientists and found that none of them read science blogs or use social networking sites for scientists. His arguments why that is so? * Time. Scientists have little time, and rather spend this time in the laboratory or reading papers * Trust.

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Nature News this week reports that This extremely embarrassing story is fortunately no longer possible. The German Kultusministerkonferenz decided on March 6 (text in German) to allow U.S. PhDs to call themselves Dr. in Germany. Until this story evolved, I didn't even know that this is an issue.