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Getting Genetics Done

Getting Things Done in Genetics & Bioinformatics Research
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AnnouncementsGgplot2BiologieEnglisch
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Autor Stephen Turner

Hadley Wickham, creator of the previously mentioned R plotting system ggplot2 and author of a forthcoming book from Springer, is teaching a workshop in data visualization using R, ggplot2, and GGobi. Unfortunately this workshop conflicts with IGES and ASHG this year, but he mentioned the possibility of holding a workshop here at Vanderbilt if there is enough interest.

Journal ClubBiologieEnglisch
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Autor Stephen Turner

Here are citations for the articles discussed at our most recent meeting (July 31). Our next meeting is scheduled for August 14.~JuliaBogdanowicz W, Allen M, Branicki W, Lembring M, Gajewska M, Kupiec T. Genetic identification of putative remains of the famous astronomer Nicolaus Copernicus.

NewsBiologieEnglisch
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Autor Stephen Turner

That's the title of a good article published yesterday in the New York Times about the emergence of statistics being in huge demand in the career market, becoming "the sexy job in the next 10 years" as Google's chief economist puts it. Now I just need to find one of these don't drink and derive t-shirts...For Today’s Graduate, Just One Word: StatisticsGetting Genetics Done by Stephen Turner is licensed under a Creative Commons Attribution (CC

PubMedSearchWeb AppsBiologieEnglisch
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Autor Stephen Turner

I've used this a little bit recently. Pubget indexes essentially everything that PubMed does, except you get the PDF you're looking for right away. Lots of other useful tools as well. I sent one email to the Pubget team and CC'd the biomedical library, and a few days later they've worked it out so PubGet recognizes Vanderbilt's subscriptions.

Journal ClubBiologieEnglisch
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Autor Stephen Turner

Here are citations for the articles discussed at our most recent meeting (July 17). Our next meeting is scheduled for July 31.~JuliaBianconi G, Pin P, Marsili M. Assessing the relevance of node features for network structure.

RBiologieEnglisch
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Autor Stephen Turner

It took me a while to figure this out, so I thought I'd share. I have a dataframe with millions of observations in it, and I want to estimate a density distribution, which is a memory intensive process. Running my kde2d function on the full dataframe throws and error -- R tries to allocate a vector that is gigabytes in size. A reasonable alternative is to run the function on a smaller subset of the data.

GWASVisualizationBiologieEnglisch
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Autor Stephen Turner

***Update Monday, November 09, 2009: The sma package is no longer available on CRAN.  See this updated post for making QQ-plots in R using ggplot2.*** Nearly everyone who has read a paper on a genome-wide association study should now be familiar with the QQ-plot.

Ggplot2RRecommended ReadingVisualizationBiologieEnglisch
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Autor Stephen Turner

As far as I know there are 3 different systems for producing figures in R: (1) base graphics, included with R, (2) the lattice package, and (3) ggplot2, one of the newer plotting systems which is, according to the creator Hadley Wickham, "based on the grammar of graphics, which tries to take the good parts of base and lattice graphics and none of the bad parts.

NewsBiologieEnglisch
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Autor Stephen Turner

Last week personal genomics giant 23andMe launched Research Revolution, a new project aiming to recruit 1000 study participants for each of ten complex diseases, including Migraines, Psoriasis, several cancers, and autoimmune diseases.

NewsBiologieEnglisch
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Autor Stephen Turner

Yesterday President Barack Obama announced his intent to appoint former leader of the Human Genome Project, discoverer of delta-F508, and all around science rockstar Francis Collins as the director of the National Institutes of Health.In his statement, Obama noted: "The National Institutes of Health stands as a model when it comes to science and research.