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FunGarminRstatsRunningBiologieEnglisch
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As 2021 draws to a close, it’s time to check back in on a previous post. As a recap, Garmin Connect offered four challenges to run 3 x 505 km and 1 x 505 km, one in each of the four quarters of 2021. Completing all four would mean running 2021 km in 2021 . I used an R script to check my progress throughout the year (available here). Each quarter gave a set of results, the final set for the whole of 2021 is shown here.

MusicITunesBiologieEnglisch
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In early December, Spotify users received a list, known as Spotify Wrapped, of the tracks they listened to most in 2021. As a committed non-streamer, I was a bit envious of these lists; so I decided to assemble my own list using my Music database. This was possible by comparing two snapshots of my Music database in xml format* that were taken in 2020 and yesterday.

ComputingScienceCell BiologyCodeColocalisationBiologieEnglisch
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Quantifying the degree of colocalisation of two signals in microscopy images is very tricky. Lots has been written on this topic, including in my book The Digital Cell. The focus of this post is on visualising colocalisation . One way to look at colocalisation is two think about two sets of objects and how many of each set overlap. This is sometimes referred to as co-occupancy or object-based colocalisation .

Adventures In CodeComputingFunChallengeProgrammingBiologieEnglisch
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In a previous post, I described a coding challenge sent to me by my colleague. Here is the challenge again: My solution was… let’s say… over-engineered. He did tell me that the winner (the challenge was set in an international coding competition) solved it in a ridiculously short time. He didn’t tell me how short which I think would have led me to take a different approach.

Adventures In CodeComputingFunChallengeIgorBiologieEnglisch
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A colleague sent me a coding challenge. This is a short post to describe how I tackled it. Edit: a follow-up post is here. This is the challenge: With an eye on b, and since I code fastest in Igor, I went with Igor over python or R. I knew this would lose me major points for c since Igor code is not very compact. It took me 22 minutes to write a solution, slowed down a bit by helping a small person with their homework.

ComputingFfmpegFLACMp3MusicBiologieEnglisch
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A quick tech tip. I usually use Audacity for converting audio files and I have a few simple macros set up in there to make life easy. I had some opus music files which do not play in Apple’s Music app and therefore needed converting to MP3 format. Annoyingly, Audacity 3.1.2 on macOS does not currently import opus files, so I needed to find an alternative. The command line tool ffmpeg can be used to convert audio files. So how can we do it?

Adventures In CodeFunMusicDiscogsPubMedBiologieEnglisch
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Some journals sound like they should be bands. Whereas some journal titles ARE in fact the same as band names. I wondered… how many journal titles are also band names. Let’s find out! The journals cited in PubMed could be downloaded as a text file from here. This list includes every MEDLINE journal – even defunct ones – as well as non-MEDLINE journals where content is is in PMC. This will do for now, but is obviously limited.

ScienceBioRxivCell BiologyClathrinCryoEMBiologieEnglisch
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A new paper means a new paper explainer. This post is all about our new paper on clathrin assembly. Some background info Endocytosis is the way that cells take up material from the outside world. The cell can make tiny vesicles that bud inwards from the cell surface and pinch off to travel inside the cell. This process is important for lots of things that cells do, so there is a lot of interest in how endocytosis works.