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Biopragmatics

Unraveling complex biology with biological knowledge graphs. Content licensed under CC BY 4.0.
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BioregistrySemantic WebPydanticFastapiPythonScienze naturaliInglese
Pubblicato
Autore Charles Tapley Hoyt

Using Pydantic for encoding data models and FastAPI for implementing APIs on top of them has become a staple for many Python programmers.

BooksScienze naturaliInglese
Pubblicato
Autore Charles Tapley Hoyt

I finally got back into reading! Over winter break 2022, I started the Stormlight Archive then followed up in 2023 by reading the entirety of Brandon Sanderson’s Cosmere , as well as a some other fantasy, science fiction, and literary fiction. Here’s the list.

UmlsReproducibilityScienze naturaliInglese
Pubblicato
Autore Charles Tapley Hoyt

The Unified Medical Language System (UMLS) is a widely used biomedical and clinical vocabulary maintained by the United States National Library of Medicine. However, it is notoriously difficult to access and work with due to licensing restrictions and its complex download system. In the same vein as my previous posts about DrugBank and ChEMBL, this post describes open source software I’ve developed for downloading and working with this data.

CheminformaticsReproducibilityScienze naturaliInglese
Pubblicato
Autore Charles Tapley Hoyt

I’ve been working on improving reproducibility in the field of cheminformatics for some time now. For example, I’ve written posts about making data from DrugBank and ChEMBL more actionable. Over the last year, I’ve been preparing a concept with the editors of the Journal of Cheminformatics on how to include an assessment of reproducibility to reviews of manuscripts submitted to the journal.

WikidataBibliometricsScienze naturaliInglese
Pubblicato
Autore Charles Tapley Hoyt

Today’s short post is about three SPARQL queries I wrote to get bibliometric information about journals and publishers out of Wikidata. Each of the following queries can be readily copy-pasted into the Wikidata Query Service and run in the browser.

WikidataBibliometricsScienze naturaliInglese
Pubblicato
Autore Charles Tapley Hoyt

I was recently nominated for the International Society for Biocuration’s Excellence in Biocuration Early Career Award (results will be announced on June 14 th !). This made me curious about how to model nominations and awards on Wikidata. In this post, I’ll describe how to curate awards, nominations, recipients, and how to make SPARQL queries to get them.

CuriesArksN2tPidsScienze naturaliInglese
Pubblicato
Autore Charles Tapley Hoyt

Archival Resource Keys (ARKs) are flavor of persistent identifiers like DOIs, URNs, and Handles that have the benefit of being free, flexible with what metadata gets attached, and natively able to resolve to web pages. Name-to-Thing (N2T) implements a resolver for a variety of ARKs, so this blog post is about how that resolver can be re-implemented with the curies Python package. In a lot of ways, ARKs look and act like CURIEs.

BioregistryOboOntologiesScienze naturaliInglese
Pubblicato
Autore Charles Tapley Hoyt

Several controlled vocabularies and ontologies that aren’t themselves OBO Foundry ontologies use unsanctioned OBO PURLs. This post is about how to use the Bioregistry to identify which resources are doing this and to give some insight into how we arrived in this situation. Background on the OBO Foundry The OBO Foundry is a set of independent, interoperable biomedical ontologies that aspire to using shared development principles.