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Data driven blogging from the GigaScience editors
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Open AccessPublishingConferencesGuest PostOpen DataBiologiaInglese
Pubblicato

Open Science has emerged into the mainstream, primarily due to concerted efforts from various individuals, institutions, and initiatives. This small, focused gathering brought together several of those community leaders.  The purpose of the meeting was to define common goals, discuss common challenges, and coordinate on common efforts.

BiologyCactusCrowdfundingGenomicsGuest PostBiologiaInglese
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Following our efforts promoting open science and “community genomics” projects such as the “Peoples Parrot” ** and Azolla “crowdfernded” genome , today we have a guest posting from Peng Jiang and Hui Guo at the University of Georgia covering their crowdfunding efforts to** sequence the first Cactus genome .  While

TechnologyBig DataGeneticsGenomicsGWASBiologiaInglese
Pubblicato

The software application PLINK is one of the most widely used tools in bioinformatics, particularly for genome-wide association studies (GWAS) that look at genetic variants in different individuals to see if any variant is associated with a trait. With the advent of the thousand dollar genome, the computational demands being made on such programs are exploding.

Open AccessAvian Phylogenomics ProjectBig DataBirdsCreative CommonsBiologiaInglese
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Tītitipounamu, Rifleman, female (left) and male (right) Our New Zealand based Commissioning Editor, Nicole Nogoy, was asked by Creative Commons Aotearoa (New Zealand) to write a guest blog on open licensing from a Kiwi perspective. Being big users and fans of their licenses we were happy to oblige.

BiologyTechnologyBGIBig DataGenomicsBiologiaInglese
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*The field of synthetic biology, designing and building engineered biological systems through DNA synthesis and genetic engineering, is rapidly moving to a genome scale. In a similar trajectory to genomic sequencing and genome projects two decades ago, it has moved from engineering single genes, entire synthetic bacterial genomes (J Craig Venter’s notorious “Synthia”), to the eukaryotic organism stage.

HealthDisease OutbreaksEbolaGuest PostInfectious DiseaseBiologiaInglese
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Following from his guest blog in October on “Approaches and resources to slow the spread of infection”, Michael Dean from the Center of Cancer Research at the NIH uses his data oriented approach to give an update of where the Ebola epidemic is. While there may be less media coverage (apart from in the UK), this doesn’t relate to the situation on the ground.

TechnologyHeart DiseaseMRIOpen DataOpen SourceBiologiaInglese
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Sheer Heart Attack Diagnosis is key to beginning treatment for preventing coronary heart disease, the most common cause of heart attacks. One useful tool in the fight against this leading killer is magnetic resonance imaging, which allows the direct examination of blood flow to the myocardium of the heart.

Open AccessTechnologyBioinformaticsDiseasesMedical DataBiologiaInglese
Pubblicato

Take a ride down chromosome highways with a novel web-based platform that allows sharing of private genetic data while maintaining privacy through a colourful dynamic visualization tool. The Human Genome Project offered new hope that discovering the genetic determinants which mediate chronic disease susceptibility would lead to new avenues for drug development and targeted therapy, yet over decade later the is disappointment