We are pleased to announce the release of BioRuby 1.5.0. This new release includes support of recent Ruby versions (Ruby 2.0.0, 2.1 and 2.2), improvement of codes, and bug fixes. Here is a brief summary of changes. Ruby 2.0.0, 2.1, 2.2 support. Some features are removed because of remote service discontinuance or difficulty of code maintenance. Refactoring of code. Bio::SPTR is renamed as Bio::UniProtKB. Bug fixes.