Apologies for the long hiatus: we've had some health issues in the family, and startup life has been particularly overwhelming.

In Wednesday’s post, I wrote that “traditional physical organic chemistry is barely practiced today,” which attracted some controversy on X. Here are some responses:

In this post, I’m trying something new and embedding calculations on Rowan alongside the text.

(Previously: 2022) #1. Tony Fadell, Build #2. Giff Constable, Talking To Humans #3. Ben Horowitz, The Hard Thing About Doing Hard Things #4. Dale Carnegie, How To Win Friends And Influence People Sounds Machiavellian, but actually quite wholesome: a “dad book,” as my friend

“And I took the little scroll from the hand of the angel and ate it.

I took a pistol course in undergrad, and while I was a poor marksman I enjoyed the experience.

“Like arrows in the hand of a warrior are the children of one's youth.” –Psalm 127:4

Quantum computing gets a lot of attention these days. In this post, I want to examine the application of quantum computing to quantum chemistry, with a focus on determining whether there are any business-viable applications today.

In 2019, ChemistryWorld published a “wish list” of reactions for organic chemistry, describing five hypothetical reactions which were particularly desirable for medicinal chemistry.

(in the spirit of Dale Carnegie and post-rat etiquette guides)

“A cord of three strands is not easily broken.” —Ecclesiastes 4:12