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Getting Genetics Done

Getting Things Done in Genetics & Bioinformatics Research
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Recommended ReadingBiologíaInglés
Publicado
Autor Stephen Turner

An international team led by Sarah Tishkoff, in collaboration with our own Scott Williams, and former CHGR member Jason Moore, published yesterday in Science the largest, most comprehensive characterization of genetic variation in over 100 different African populations.

RTutorialsBiologíaInglés
Publicado
Autor Stephen Turner

A reader asked yesterday how you would merge data from two different files. For example, let's say you have a ped file with genotypes for individuals, and another file that had some other data for some of the individuals in the pedfile, like clinical or environmental covariates.

Recommended ReadingBiologíaInglés
Publicado
Autor Stephen Turner

From a News and Views article in Nature Genetics, following up the recently mentioned sequencing effort for X-linked mental retardation:Nature Genetics: X-cess of variants in XLMRGetting Genetics Done by Stephen Turner is licensed under a Creative Commons Attribution (CC BY) License.

ProductivitySoftwareWritingBiologíaInglés
Publicado
Autor Stephen Turner

When you need to focus and get some serious writing done, it may be a good idea to ditch your word processor and go with plain text instead. Save all your formatting and spell-checking to do later in one step. I just tried this out on a review article I needed to write and found it much easier to concentrate without all of MS Word's squiggly underlining, autocorrecting, autoformatting, and fancy toolbar buttons begging to be clicked.

BioinformaticsWeb AppsBiologíaInglés
Publicado
Autor Stephen Turner

I saw a demonstration of this tool at the workshop on network analysis I announced last week. Genes2Networks draws from a large background network consisting of several experimentally verified mammalian protein interaction databases. It will take a list of genes you provide as seed genes and identify all interacting genes that fall on paths through the background network between them.

NewsRecommended ReadingSequencingBiologíaInglés
Publicado
Autor Stephen Turner

Amidst the fallout of an academic discussion over the worth of GWA studies followed by several gloomy and scathing articles in the popular press, came this paper in Nature Genetics. In summary, the investigators sequenced all the coding DNA on the X-chromosome in families affected with an evidently X-linked mental retardation phenotype.

AnnouncementsBiologíaInglés
Publicado
Autor Stephen Turner

Save yourself a few keystrokes the next time you visit GGD. Going to gettinggeneticsdone.com will now automatically redirect you to the blogspot address. If you've bookmarked the site or subscribed to the site's feed with RSS, everything will still work.Getting Genetics Done by Stephen Turner is licensed under a Creative Commons Attribution (CC BY) License.

AnnouncementsBioinformaticsBiologíaInglés
Publicado
Autor Stephen Turner

Avi Ma'ayan, Ph.D., Assistant Professor in the Department of Pharmacology and Systems Therapeutics of Mount Sinai School of Medicine, will present "Network Analysis in Systems Biology", at 10:00 am on Wednesday, April 22 in Room 206 PRB.Following the lecture, Dr. Ma’ayan will hold a series of one-hour interactive workshops on "Computational Methods for Analyzing Lists of Genes/Proteins and Building Networks in Systems Biology," which will

GWASNewsRecommended ReadingBiologíaInglés
Publicado
Autor Stephen Turner

Here are four interesting and provocative articles in New England Journal of Medicine:David Goldstein: Common Genetic Variation and Human TraitsJoel Hirschhorn: Genomewide Association Studies — Illuminating Biologic PathwaysPeter Kraft and David Hunter: Genetic Risk Prediction — Are We There Yet?John Hardy &

LinuxBiologíaInglés
Publicado
Autor Stephen Turner

I briefly mentioned "time" in the previously posted Linux command line cheat sheet, but I can't overstate its utility especially for ACCRE/Vampire users. The time command does exactly what it sounds like: it times exactly how long it takes to run anything at the command line. And it couldn't be easier to use.