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Henry Rzepa's Blog

Henry Rzepa's Blog
Chemistry with a twist
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HypervalencyCChemical BondingChemistryFree EnergyCiencias QuímicasInglés
Publicado

Another post inspired by a comment on an earlier one; I had been discussing compounds of the type I.In (n=4,6) as possible candidates for hypervalency. The comment suggests the below as a similar analogue, deriving from observations made in 1989.

Interesting ChemistryCity: LondonCountry: United KingdomRoyal Horticultural SocietyWildflowerCiencias QuímicasInglés
Publicado

Last year, I showed photos of wildflower meadows in west London close to where we live, evolving as the seasons changed. Today we hear the announcement that London itself is set be declared the world’s first National Park City in 2019.

GeneralChemistryDerek LoweDeuterated DrugDrugCiencias QuímicasInglés
Publicado

I don’t normally write about the pharmaceutical industry, but I was intrigued by several posts by Derek Lowe (who does cover this area) on the topic of creating new drugs by deuterating existing ones. Thus he covered the first deuterated drug receiving FDA approval last year, having first reviewed the concept back in 2009.