I liked Steve Krouse’s essay, “Vibe code is legacy code.” It helped crystalize some half-baked thoughts I have on vibe coding. Here’s an excerpt.Subscribe now Maintainability and vibe are inversely correlated I’ve been using GitHub copilot and chatbots for code for years, and I’ve written about them a lot here.

There’s something quietly radical about the idea that a junior scientist—someone who’s never designed a CRISPR experiment before—can now walk into a wet lab and, on their very first attempt, edit the genome of a human cancer cell with precision and purpose.

The Genomic Standards Consortium (GSC) recently convened for the GSC25 meeting in Cambridge, UK. Bringing together leading researchers, data scientists, and genomics professionals from around the world. Held from July 28-August 1, GSC25 marked a significant milestone – celebrating two decades of advancing genomic data standards while charting the course for the next 20 years.

Today, our article “The entities enabling scientific fraud at scale are large, resilient, and growing rapidly” was published in PNAS . The article will only be fully open-access in six months (damn you, publishing fees), but I’ve made the PDF available here (you can download the supplementary materials on the PNAS page). I’ll use this blog post to summarize and opine (what I write here reflects my own thinking about this study

por Fernando Aguayo El señor Matthew Fontaine Maury llegó a México el día 28 de mayo de 1865. Apenas unas semanas después, era parte de la Academia de Ciencias y Literatura, en tanto que la Sociedad Mexicana de Geografía y Estadística lo aceptaba como socio honorario.

Inspired by related writings from Scott Alexander, who is funnier than me.

The Rogue Scholar science blog archive uses DOIs to uniquely identify blog posts with meaningful metadata. This enables tracking citations of scholar blog posts in the scholarly literature using traditional citation tracking methods rather than altmetrics. Initially launched as a Rogue Scholar service six months ago, citation tracking has launched to production this week.

The Ontology Lookup Service (OLS) is now indexing dense embeddings for ontology terms constructed from term labels, synonyms, and descriptions using LLMs. I maintain a Python client library for the OLS (ols-client) and was recently asked to implement a wrapper to the OLS’s API endpoint that exposes these embeddings.

I have finally opened a Posts section on my website! Every post should now automatically get a DOI. This is something I have wanted to do for a long time, largely inspired by the tireless and consistent example set by Egon Willighagen (Willighagen 2024a, 2024b, 2025). It was today’s post of (Fenner 2025) that finally motivated me to look into it again.

The American Society for Microbiology (ASM) has earned recognition in Crossref’s Participation Reports for its exceptional metadata coverage among large publishing members––an achievement built on intentional change, technical investment, and collaborative work.

I recently gave a 30-minute talk at the Librarian Futures Virtual Summit, and for the topic of "AI-powered search," I decided to play devil's advocate.