Every publication is assembling year-end lists of their selection of the best albums of the year. Well, quantixed did not want to miss out on the fun, so I came up with a list of my favourite 20 albums released in 2021.

Quantifying the degree of colocalisation of two signals in microscopy images is very tricky. Lots has been written on this topic, including in my book The Digital Cell. The focus of this post is on visualising colocalisation . One way to look at colocalisation is two think about two sets of objects and how many of each set overlap. This is sometimes referred to as co-occupancy or object-based colocalisation .

In a previous post, I described a coding challenge sent to me by my colleague. Here is the challenge again: My solution was… let’s say… over-engineered. He did tell me that the winner (the challenge was set in an international coding competition) solved it in a ridiculously short time. He didn’t tell me how short which I think would have led me to take a different approach.

A colleague sent me a coding challenge. This is a short post to describe how I tackled it. Edit: a follow-up post is here. This is the challenge: With an eye on b, and since I code fastest in Igor, I went with Igor over python or R. I knew this would lose me major points for c since Igor code is not very compact. It took me 22 minutes to write a solution, slowed down a bit by helping a small person with their homework.

A quick tech tip. I usually use Audacity for converting audio files and I have a few simple macros set up in there to make life easy. I had some opus music files which do not play in Apple’s Music app and therefore needed converting to MP3 format. Annoyingly, Audacity 3.1.2 on macOS does not currently import opus files, so I needed to find an alternative. The command line tool ffmpeg can be used to convert audio files. So how can we do it?

Some journals sound like they should be bands. Whereas some journal titles ARE in fact the same as band names. I wondered… how many journal titles are also band names. Let’s find out! The journals cited in PubMed could be downloaded as a text file from here. This list includes every MEDLINE journal – even defunct ones – as well as non-MEDLINE journals where content is is in PMC. This will do for now, but is obviously limited.

In-person science meetings are returning. To the introverts and the carers, the time-poor and the cash-strapped, the climate-conscious and the travel-phobic, the visa-challenged and the real-coffee appreciators, we had our chance; but in-person science meetings are returning.

A new paper means a new paper explainer. This post is all about our new paper on clathrin assembly. Some background info Endocytosis is the way that cells take up material from the outside world. The cell can make tiny vesicles that bud inwards from the cell surface and pinch off to travel inside the cell. This process is important for lots of things that cells do, so there is a lot of interest in how endocytosis works.

We have a new paper out! This post is to describe what our paper is about. The paper is free to read, so please take a look if you are interested. Gabrielle Larocque, Daniel J. Moore, Méghane Sittewelle, Cansu Kuey, Joseph H.R. Hetmanski, Penelope J. La-Borde, Beverley J. Wilson, Nicholas I. Clarke, Patrick T. Caswell &

There are perennial topics of discussion on Science Twitter. An example of this is: should figures be at the end of a manuscript are interspersed in the text. These topics tend not to be resolved because there are strong arguments (and personal preferences) on each side. I am not sure whether it is even possible to get people to agree with you using reasoned argument on Twitter.

Back in 2015, I wrote a guide to using Trello for lab organisation. I figured it was time for an update because a few things have changed since then and the topic of using Trello for larger labs came up on Twitter. Note that other kanban-style software is available. Basic Trello setup I set up a lab workspace and invited everyone in the team to it. We have three main boards (described below) that everyone in the workspace can see.