This post describes an issue I’ve had with writing correct types when using PEP-696 defaults in typing.TypeVar. I posted the exploration in a companion repository on GitHub. The motivation behind this comes from my work in biomedical data integration and the semantic web.

Repurposed Appalachia Series ​ Being perched between 4,100 and 4,223 feet on the rugged spine of Stone Mountain, the modern High Knob Observation Tower greets each sunrise with a gleam of galvanized steel on sandstone. Long before it became a scenic waypoint for motorists and hikers near Norton, Virginia, High Knob’s summit served an urgent purpose: keeping watch for wildfire.

Introduction When we exercise, our hearts run faster, which is associated with a decrease in the time between heartbeats. This time between heartbeats is also known by R-R intervals. If you have ever seen an electrocardiogram (EKG) curve before, each time your heart pumps you’ll see a small spike in your EKG;

NB: This is part of research that will be published in a special issue of Popular Culture Studies Journal focusing upon Star Trek: Enterprise which I am guest-editing (CFP open until 15 June). As a lifelong fan of the Star Trek franchise and a lifelong queer person (even if it took me a few decades to figure it out),[i] it is hard to overstate the joy I felt upon learning that Star Trek: Lower Decks (Paramount+

In a world where biology powers geopolitics, one analyst must help rewire the United States into a resilient, decentralized biomanufacturing force.

Forgotten Appalachia Series Tucked away in downtown Harlan, Kentucky, an unassuming patch of grassy ground at 206 East Clover Street conceals one of the county’s oldest and most intriguing burial grounds. Once hidden behind the walls of a crumbling Ford dealership building, this “secret cemetery” has only recently come back into public view—and with it, the faded chapter of Harlan’s early settlers and their storied feuds.

Sponsors make Crossref membership accessible to organisations that would otherwise face barriers to joining us. They also provide support to facilitate participation, which increases the amount and diversity of metadata in the global Research Nexus. This in turn improves discoverability and transparency of scholarship behind the works.

Reposted from the original at https://blog.stephenturner.us/p/r-450-bioconductor-321. Faster package installation, import only the functions you want with use(), built-in Palmer penguins data, grep values shortcut, and lots of new bioinformatics packages in Bioconductor ... R 4.5.0 was released last week, and Bioconductor 3.21 came a few days later.

R 4.5.0 was released last week, and Bioconductor 3.21 came a few days later. You can read the R release notes here and the Bioconductor 3.21 announcement here.

ChEMBL periodically curates clinical trial information into its DRUG_INDICATION table. However, there’s some weird inconsistencies in the way it references disease concepts in external vocabularies. This blog post is an exploration of that table.

Crossposted from the Knowledge Commons team blog. Over the last several weeks, we've seen colleagues of ours across the country posting about the direct impacts they're experiencing of the current attacks on the National Endowment for the Humanities, including sudden and extensive terminations of previously awarded grants.