Michael in a comment here on the mechanism of the Masamune-Bergman reaction notes that when it occurs as part of the Calicheamicin (an antibody-drug conjugate or ADC) version of this mechanism, a pre-step is first necessary.
(please cite this post as https://doi.org/10.59350/zme5j-0jp45) I previously wrote a blog post, “There’s no such thing as sustainable research software,” trying to be somewhat provocative. In it I wrote: However, after thinking about this a bit more, I don’t think this means we shouldn’t try.
Good morning my friends, I've spent the last few weeks deep in the weeds of AI and biotechnology policy (that’s a lie, I’ve spent far more than a few weeks, but humor me), and I've got to tell you - the latest progress never ceases to amaze me no matter how much time I spend thinking about the topic.
How to cite: Page, R. (2024). Internet Archive as a single point of failure https://doi.org/10.59350/1r3m1-c5e22 Just a placeholder to mark the ongoing impact of the Internet Archive being attacked (see here, here and here for details). The impact of this on the Biodiversity Heritage Library (BHL) has been huge, and reveals the extent to which BHL depends on the Archive.
Despite being based in Japan, I tend not to write directly about it as much as I plan to. I keep meaning to address this, but have been distracted with other topics. Given that the country is in the news following the weekend’s election, I thought it might be useful to offer some reflections and context.
Chris Smeenk reviews Accelerating Expansion, by Gordon Belot
A growing trend of keeping mongooses as pets in Jamaica has raised alarms among wildlife experts and animal rights activists. While these small carnivores may seem like intriguing pets, several concerns surround their domestication and the potential ecological consequences. Understanding the Mongoose Mongooses are small to medium-sized mammals belonging to the family Herpestidae.
Exploring Colorado’s Emerging Wolf Hot Spot Colorado is at the forefront of an ecological phenomenon as wolves begin to establish a significant presence in parts of the state. While the resurgence of this magnificent predator is a testament to successful conservation efforts, it also raises significant concerns among ranchers.
Open Science doesn’t make publishing easier. That that’s all for the better: our research efforts are complex, so why should the publishing be. Sure, I am not talking about references formatting or moving the Methods section to the right location, or some silly statement that all authors agree with the manuscript when you are the only author.
Once again, we’re looking to grow our editorial team at JOSS! Since our launch in May 2016, our existing editorial team has handled nearly 4100 submissions (~2700 published at the time of writing, 340 under review) and the demand from the community continues to be strong. JOSS now consistently publishes 40-45 papers per month, and this is gradually increasing.
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